Abstract Title:

Potential protective effects of red yeast rice in endothelial function against atherosclerotic cardiovascular disease.

Abstract Source:

Chin J Nat Med. 2019 Jan ;17(1):50-58. PMID: 30704624

Abstract Author(s):

Shu-Jun Feng, Zhi-Han Tang, Ying Wang, Xin-Ying Tang, Tao-Hua Li, Wei Tang, Ze-Min Kuang

Article Affiliation:

Shu-Jun Feng


Atherosclerotic cardiovascular disease (ASCVD) is the deadliest disease in the world, with endothelial injury occurring throughout the course of the disease. Therefore, improvement in endothelial function is of essential importance in the prevention of ASCVD. Red yeast rice (RYR), a healthy traditional Chinese food, has a lipid modulation function and also plays a vital role in the improvement of endothelial reactivity and cardiovascular protection; thus, it is significant in the prevention and treatment of ASCVD. This article reviews the molecular mechanisms of RYR and its related products in the improvement of endothelial function in terms of endothelial reactivity, anti-apoptosis of endothelial progenitor cells, oxidative stress alleviation and anti-inflammation.

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