Article Publish Status: FREE
Abstract Title:

Precision Light for the Treatment of Psychiatric Disorders.

Abstract Source:

Neural Plast. 2018 ;2018:5868570. Epub 2018 Jan 11. PMID: 29593784

Abstract Author(s):

Sevag Kaladchibachi, Fabian Fernandez

Article Affiliation:

Sevag Kaladchibachi


Circadian timekeeping can be reset by brief flashes of light using stimulation protocols thousands of times shorter than those previously assumed to be necessary for traditional phototherapy. These observations point to a future where flexible architectures of nanosecond-, microsecond-, and millisecond-scale light pulses are compiled to reprogram the brain's internal clock when it has been altered by psychiatric illness or advanced age. In the current review, we present a chronology of seminal experiments that established the synchronizing influence of light on the human circadian system and the efficacy of prolonged bright-light exposure for reducing symptoms associated with seasonal affective disorder. We conclude with a discussion of the different ways that precision flashes could be parlayed during sleep to effect neuroadaptive changes in brain function. This article is a contribution to a special issue oncurated by editors Shimon Amir, Karen Gamble, Oliver Stork, and Harry Pantazopoulos.

Study Type : Human Study
Additional Links
Therapeutic Actions : Light Therapy : CK(496) : AC(83)

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