Impact of Antibiotics on Necrotizing Enterocolitis and Antibiotic-Associated Diarrhea.
Gastroenterol Clin North Am. 2017 Mar ;46(1):61-76. PMID: 28164853
Michael A Silverman
Antibiotic treatment alters the composition and metabolic function of the intestinal microbiota. These alterations may contribute to the pathogenesis of necrotizing enterocolitis (NEC) and antibiotic-associated diarrhea (AAD). Recent studies are beginning to unravel the contribution of specific groups of microbes and their metabolic pathways to these diseases. Probiotics or other microbiota-targeted therapies may provide effect strategies to prevent and treat NEC and AAD.