Abstract Title:

Probiotics reduce anxiety-related behavior in zebrafish.

Abstract Source:

Heliyon. 2020 May ;6(5):e03973. Epub 2020 May 14. PMID: 32435716

Abstract Author(s):

David G Valcarce, Juan M Martínez-Vázquez, Marta F Riesco, Vanesa Robles

Article Affiliation:

David G Valcarce


There is increasing evidence that gut microbiome could have effects on neurological processes and on behavior. In this study we used the novel tank test (NTT) to analyze zebrafish exploring behavior after four months' supplementation with probiotics with probed antioxidant and anti-inflammatory properties. Results showed that prolonged ingestion ofCECT8361 andCECT7347 significantly alters the swimming pattern and mean swimming speed in the zebrafish model. After treatment, zebrafish strongly reduced their bottom-dwelling geotactic behavior when placed in a new tank, which could be correlated to a lower state of anxiety.

Study Type : Animal Study

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