Propolis suppresses angiogenesis. - GreenMedInfo Summary

Abstract Title:

Propolis suppresses tumor angiogenesis by inducing apoptosis in tube-forming endothelial cells.

Abstract Source:

Biosci Biotechnol Biochem. 2008 Sep 7. PMID: 18776674

Abstract Author(s):

Toshiro Ohta, Kazuhiro Kunimasa, Tomomi Kobayashi, Miwa Sakamoto, Kazuhiko Kaji


Full Citation: "We have reported that propolis suppresses tumor-induced angiogenesis in vivo and in vitro, but antiangiogenic mechanism of propolis at cellular level remains unclear. In this study, we observed that propolis not only inhibited tube formation but also induced apoptosis of endothelial cells. These results suggest that propolis exerts its antiangiogenic effects at least in part through induction of apoptosis."

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