Article Publish Status: FREE
Abstract Title:

Protective effect of anthocyanin from Lonicera Caerulea var. Edulis on radiation-induced damage in mice.

Abstract Source:

Int J Mol Sci. 2012 ;13(9):11773-82. Epub 2012 Sep 18. PMID: 23109882

Abstract Author(s):

Haitian Zhao, Zhenyu Wang, Fengming Ma, Xin Yang, Cuilin Cheng, Lei Yao

Article Affiliation:

Haitian Zhao


The radioprotective effect of anthocyanin extracted from Lonicera caerulea var. edulis (ALC), was studied in ICR mice. Different doses of ALC were intragastrically administered to mice once a day, prior to radiation. After two weeks, the mice received a one-time 5 Gy whole body (60)Coγ radiation. The spleen index, thymus index, activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px), malondialdehyde (MDA) content, and glutathione (GSH) content in liver tissue were measured. Compared with the radiation control group, the levels of MDA in all ALC treated groups decreased significantly (p<0.05). Moreover, the GSH content, activities of SOD and GSH-Px in liver tissue were enhanced significantly (p<0.05) in all ALC groups. These results demonstrate that ALC may be a potential radioprotector, and a further study of the molecular mechanism is needed for further application.

Print Options

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.