Article Publish Status: FREE
Abstract Title:

Protective effect of aqueous spinach () extract on spinal cord ischemia-reperfusion injury in rats.

Abstract Source:

Vet Res Forum. 2018 ;9(2):187-191. Epub 2018 Jun 15. PMID: 30065808

Abstract Author(s):

Gholam Hossein Farjah, Masoumeh Mohammad Pour, Mohammad Hassan Khadem-Ansari, Mojtaba Karimipour, Bagher Pourheidar

Article Affiliation:

Gholam Hossein Farjah


Operation on the thoraco-abdominal aorta may lead to paraplegia or paraparesis is after spinal ischemia/reperfusion (I/R) injury. In this study, we investigated the protective effect of the spinach extract on spinal cord I/R injury. Thirty-five male Sprague-Dawley rats were divided into five groups: Intact, sham surgery, normal saline (NS), low dose spinach extract (20 mg kg), high dose spinach extract (50 mg kg). Neurological function, biochemical and histological evaluations were performed in 72 hr after ischemia. The mean motor deficit index scores of the spinach extract groups were significantly lower than in the NS group at 72hr after spinal cord ischemia. In addition, Spinach extract groups significantly increased plasma level of total antioxidative capacity and decreased the plasma level of malondialdehyde than the NS group. The spinach extract groups displayed a significantly large number of normal motor neurons compared with the NS group. In conclusion, the present study showed that the spinach extract may preserve more neurons in a rat model of spinal cord I/R injury.

Study Type : Animal Study
Additional Links

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.