Abstract Title:

The protective role of carnosic acid in ischemic/reperfusion injury through regulation of autophagy under T2DM.

Abstract Source:

Exp Biol Med (Maywood). 2019 May ;244(7):602-611. Epub 2019 Apr 4. PMID: 30947537

Abstract Author(s):

Min Hu, Tianyu Li, Zixiang Bo, Feixiang Xiang

Article Affiliation:

Min Hu


We have provided, for the first time, evidence that carnosic acid (CA) attenuates ischemia-reperfusion injury of diabetic myocardium, i.e. diabetic myocardial ischemia/reperfusion (DMI/R) injury, via enhancement of autophagy. A greater understanding of the target molecule in CA-enhanced autophagy is necessary for the development of potential chemotherapy for DMI/R injury.

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