Abstract Title:

Prunella vulgaris L: Critical Pharmacological, Expository Traditional uses and Extensive Phytochemistry: A Review.

Abstract Source:

Curr Drug Discov Technol. 2021 Feb 3. Epub 2021 Feb 3. PMID: 33538676

Abstract Author(s):

Reyaz Hassan Mir, Mohammad Faizan Bhat, Gifty Sawhney, Parveen Kumar, Nusrit Iqbal Andrabi, Majeed Shaikh, Roohi Mohi-Ud-Din, Mubashir Hussain Masoodi

Article Affiliation:

Reyaz Hassan Mir


BACKGROUND: Prunella vulgaris, family Lamiaceae also known as self-heal, has been traditionally used as an expectorant, anti-inflammatory, anti-pyretic, and anti-rheumatic. Due to widespread distribution of the plant, Vulgaris is also called 'vulgar' in Latin adjective meaning common.

OBJECTIVE: The objective of this review was to describe the relevant aspects of phytochemistry and therapeutic uses of different fractions as well as isolated compounds from Prunella vulgaris. An attempt was also made to enumerate the possible leads e.g. betulinic acid, oleanolic acid, ursolic acid, umbelliferone, scopoletin, esculetin, luteolin, homoorientin, Rosmarinic acid and cinaroside for further development.

METHOD: For peer-reviewed research literature, we undertook a structured search of bibliographic databases using a focused review question. Scientific databases such as PubMed, Scopus, Science Direct, and Google Scholar were used Results: Phytochemistry of Prunella vulgaris (PV) after a thorough literature survey revealed varied and copious metabolites, such as triterpenoids, phenolic acid, sterols, carbohydrates, coumarins, fatty acids, and volatile oils. Many of these compounds have been found to possess wide range of biological activity per se, including anti-microbial, immunosuppressive, anti-cancer, cardio-protective, anti-allergic and anti-inflammatory.

CONCLUSION: Prunella vulgaris is a medicinal plant of immense medicinal importance having a variety of compounds such as such as triterpenoids, phenolic acid, sterols, carbohydrates, coumarins, fatty acids, and volatile oils and diversity in pharmacological spectrum. The plant could be further exploited, to isolate the various biologically active constituents responsible for its activity.

Print Options

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.