Abstract Title:

Detection of antifungal activity in Portulaca oleracea by a single-cell bioassay system.

Abstract Source:

Food Chem Toxicol. 1990 Jul;28(7):483-90. PMID: 10925396

Abstract Author(s):

K B Oh, I M Chang, K J Hwang, W Mar


The antifungal activity of Portulaca oleracea extracts against hyphal growth of various fungi was evaluated in real time using an automatic single-cell bioassay system. Target organisms were the filamentous fungi Aspergillus and Trichophyton and the yeast Candida. A colony of test fungi was in contact with the assay medium, or assay medium containing plant extract, in sequence. The antifungal activity of each fraction of P. oleracea was evaluated based on the dynamic hyphal growth response curves of test fungi. A crude sample obtained by EtOAc extract showed a specific and marked activity against dermatophytes of the genera Trichophyton. Copyright 2000 John Wiley & Sons, Ltd.

Study Type : In Vitro Study
Additional Links
Pharmacological Actions : Antifungal Agents : CK(494) : AC(306)

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