Abstract Title:

Efficacy of Pycnogenol® supplementation in remission phases of Sjögren syndrome.

Abstract Source:

Minerva Cardioangiol. 2018 Oct ;66(5):543-546. PMID: 30328688

Abstract Author(s):

Roberta Luzzi, Gianni Belcaro, Shu Hu, Beatrice Feragalli, Morio Hosoi, Mark Dugall, Andrea Ledda

Article Affiliation:

Roberta Luzzi


BACKGROUND: The aim of this study was to evaluate the effects of Pycnogenol® supplementation in otherwise healthy subjects with Sjögren syndrome (SS) in a remission phase, who experienced persisting symptoms impairing their quality of life.

METHODS: The control group receiving only standard treatment was composed of 14 subjects, the supplement group included 16 subjects who used Pycnogenol® supplementation.

RESULTS: ESR and oxidative stress levels were high in all subjects at inclusion; both decreased significantly with supplementation (P<0.05). Pycnogenol® significantly improved the majority of symptoms (dry eyes and mouth dryness), diminishing the need for corticosteroids and other treatments.

CONCLUSIONS: Pycnogenol® supplementation in patients with SS in a remission phase may be effective to control inflammation and reduce symptoms.

Study Type : Human Study

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Sayer Ji
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