Article Publish Status: FREE
Abstract Title:

Rare Acetogenins with Anti-Inflammatory Effect from the Red Alga.

Abstract Source:

Molecules. 2019 Jan 29 ;24(3). Epub 2019 Jan 29. PMID: 30699968

Abstract Author(s):

Walied Mohamed Alarif, Sultan Semran Al-Lihaibi, Nahed Obaid Bawakid, Ahmed Abdel-Lateff, Hamdan Salem Al-Malky

Article Affiliation:

Walied Mohamed Alarif


Three new rare Cacetogenins (enyne derivatives⁻) were isolated from the organic extract obtained from the red alga, collected from the Red Sea. The chemical structures of the isolated compounds were established by spectroscopical data analyses. Potent anti-inflammatory effect of the isolated metabolites was evidenced by inhibition of the release of inflammatory mediators (e.g., TNF-α, IL-1β and IL-6) by employing Human Peripheral Blood Mononuclear Cells (PBMC).

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