Article Publish Status: FREE
Abstract Title:

Bilateral herpes simplex keratitis reactivation after lacrimal gland botulinum toxin injection.

Abstract Source:

Indian J Ophthalmol. 2018 May ;66(5):697-699. PMID: 29676321

Abstract Author(s):

Purvasha Narang, Swati Singh, Vikas Mittal

Article Affiliation:

Purvasha Narang


Botulinum toxin A (BTA) injections into lacrimal gland are being used for refractory epiphora due to intractable lacrimal disorders with success rates reported from 18% to 86%. Most common side effects are transient ptosis and diplopia. We report a case of a 59-year-old female injected with 2.5 units of BTA injection in each lacrimal gland for functional epiphora. The patient had a history of herpes simplex viral keratitis that was quiescent for more than 2 years. After 3 weeks, she developed reactivation of viral keratitis bilaterally, which was successfully managed with antivirals and topical steroids. Reactivation of quiescent herpes simplex keratitis is a possibility after lacrimal gland BTA and caution should be exercised in such cases.

Study Type : Human: Case Report
Additional Links
Problem Substances : Botox : CK(20) : AC(1)

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