Article Publish Status: FREE
Abstract Title:

Recommendations for the prevention of breast cancer in shift workers.

Abstract Source:

EPMA J. 2011 Dec ;2(4):351-6. Epub 2011 Dec 23. PMID: 23199173

Abstract Author(s):

Kneginja Richter, Jens Acker, Nikola Kamcev, Stojan Bajraktarov, Anja Piehl, Guenter Niklewski

Article Affiliation:

Center for sleep medicine, Klinikum Nürnberg Nord, Haus 34, Prof.-Ernst-Nathan-Straße 1, 90419 Nürnberg, Germany.


The functioning of the human body is regulated by the rhythmical change between rest and activity. The SCN (suprachiasmatic nucleus) is responsible for the central control of the biorhythm and the genetic prediction of the individual chronotype, whereas peripheral time cues such as light, social contacts and times of meals modulate the rhythmical activity of the body. Shift workers suffer from a disruption of the sleep-wake rhythm, insomnia and a lack of melatonin. These factors might trigger the development of breast cancer in female shift workers. The growing amount of data which indicate the high risk of breast cancer in female shift workers demonstrates the need for the implementation of prevention strategies against insomnia in shift workers. These strategies include regular sleep education courses on the prevention of sleep disorders in companies. The individual chronotype could be an important predictor for the adaptability to shift work.

Study Type : Human Study
Additional Links
Anti Therapeutic Actions : Shift Work : CK(179) : AC(22)

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