Abstract Title:

The effect of red beet (Beta vulgaris var. rubra) fiber on alimentary hypercholesterolemia and chemically induced colon carcinogenesis in rats.

Abstract Source:

Nahrung. 2000 Jun;44(3):184-7. PMID: 10907240

Abstract Author(s):

P Bobek, S Galbavý, M Mariássyová


The effect of diet supplemented with 5% and 15% cellulose or with alimentary hypercholesterolemia and chemically induced colon carcinoma was studied in male Wistar rats. Hypercholesterolemia was induced by a diet containing 0.3% of cholesterol and colon carcinoma was induced by treatment with dimethylhydrazine (20 mg/kg, 12 doses applied s.c. in one-week intervals). Fibrous matter isolated from red beet contained 89% fiber, of which 9% was in water soluble form. Animals were killed 14 weeks after the application of dimethylhydrazine (i.e. 26 weeks after starting on the diets). Red beet fiber diet (and not the increased cellulose intake) caused a reduction of serum cholesterol and triacylglycerol levels (by 30 and 40%, respectively) and a significant increase in the fraction of cholesterol carried in HDL. This diet induced also a significant decrease (almost by 30%) of cholesterol content in aorta.

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