Abstract Title:

Prospects for rejuvenation of aged tissue by telomerase reactivation.

Abstract Source:

Rejuvenation Res. 2010 Dec;13(6):749-54. PMID: 21226558

Abstract Author(s):

Lynne S Cox, Penelope A Mason

Article Affiliation:

Department of Biochemistry, University of Oxford, Oxford, United Kingdom. [email protected]


Human aging is associated with loss of tissue homeostasis and a greatly elevated risk of debilitating disease, with associated costs in terms of diminished quality of life for the individual and financial burdens on health-care providers. Any advances that hold out the realistic prospect of tackling age-related morbidity are therefore to be welcomed. The recent report by Jeskelioff et al. published in 2010 that telomerase reactivation in adult male mice can not only halt but actually reverse significant tissue pathologies provides a long-awaited proof of principle that it is possible to rejuvenate aged tissues. This review assesses the impact of this new work and considers possible problems and potential benefits of telomerase activation as a therapy to tackle the morbidities associated with human aging.

Study Type : Review
Additional Links

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.