Reseveratrol inhibits adenovirus type 7 replication. - GreenMedInfo Summary
[In vitro experimental study on the effect of resveratrol against several kinds of respiroviruses].
Zhong Yao Cai. 2008 Sep;31(9):1388-90. PMID: 19180966
Molecular Immunology and Antibody Engineering Center, Jinan University, Guangzhou 510632, China.
OBJECTIVE: To observe the cytopathogenic inhibitory effect of resveratrol on vary respiroviruses and explore the mechanism of resveratrol against viruses. METHODS: MDCK, A549, HEp-2 cell and MRC-5 were infected with Influenza virus type A FM1 strain, rhinovirus type R14, RS virus, AD virus type 7 separately, and the antiviral activity of resveratrol were observed. RESULTS: Resveratrol significantly inhibited cytopathogenic effect of AD virus type 7 at the concentration 120 microg/ml. No significant cytopathogenic effect of Resveratrol inhibiting Influenza virus type A FM1 strain, Rhinovirus type R14, RS virus on separate cells was observed. CONCLUSION: It is concluded that resveratrol is effective on inhibiting AD virus type 7 in vitro, however, its mechanism is needed for further study.