Article Publish Status: FREE
Abstract Title:

Extraction optimization, antioxidant activity, and tyrosinase inhibitory capacity of polyphenols from.

Abstract Source:

Food Sci Nutr. 2019 May ;7(5):1786-1794. Epub 2019 Apr 21. PMID: 31139392

Abstract Author(s):

ZiLuan Fan, Lu Li, XiaoLin Bai, Hua Zhang, QiRui Liu, He Zhang, YuJie Fu, Rumbani Moyo

Article Affiliation:

ZiLuan Fan


The objective of this research was twofold: first, to optimize the extraction process ofpolyphenols using a response surface methodology, and second, to study the antioxidant activity and tyrosinase inhibitory capacity of the polyphenols of different purities. High-speed shearing homogenization extraction was used to extract the polyphenols from. The antioxidant activity and the effect of polyphenols on tyrosinase activity were studied using free radical scavenging assay and the tyrosinase method, respectively. The optimal extraction conditions with an extraction yield of 6.96% for polyphenols were determined as follows: ethanol volume fraction 57%, shearing time 3.30 min, and solid-liquid ratio 1:58.polyphenols exhibited potent scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2, 2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), and inhibitory capacity on tyrosinase. The results suggested thatpolyphenols could be explored as a natural antioxidant and tyrosinase inhibitor.

Study Type : In Vitro Study

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