Abstract Title:

The grape antioxidant resveratrol for skin disorders: promise, prospects, and challenges.

Abstract Source:

Arch Biochem Biophys. 2011 Jan 4. Epub 2011 Jan 4. PMID: 21215251

Abstract Author(s):

Mary Ndiaye, Carol Philippe, Hasan Mukhtar, Nihal Ahmad

Article Affiliation:

Department of Dermatology, University of Wisconsin, Madison, WI 53706, USA.


Resveratrol, a phytoalexin antioxidant found in red grapes, has been shown to have both chemopreventive and therapeutic effects against many diseases and disorders, including those of the skin. Studies have shown protective effects of resveratrol against ultraviolet radiation-mediated oxidative stress and cutaneous damages including skin cancer. Because many of the skin conditions stem from ultraviolet radiation and oxidative stress, this antioxidant appears to have promise and prospects against a wide range of cutaneous disorders including skin aging and skin cancers. However, there are a few roadblocks in the way of this promising agent regarding its translation from the bench to the bedside. This review discusses the promise and prospects of resveratrol in the management of skin disorders and the associated challenges.

Study Type : Review

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