Article Publish Status: FREE
Abstract Title:

Anticancer Activity and Mechanism of Xanthohumol: A Prenylated Flavonoid From Hops (L.).

Abstract Source:

Front Pharmacol. 2018 ;9:530. Epub 2018 May 22. PMID: 29872398

Abstract Author(s):

Chuan-Hao Jiang, Tao-Li Sun, Da-Xiong Xiang, Shan-Shan Wei, Wen-Qun Li

Article Affiliation:

Chuan-Hao Jiang


It has been observed that many phytochemicals, frequently present in foods or beverages, show potent chemopreventive or therapeutic properties that selectively affect cancer cells. Numerous studies have demonstrated the anticancer activity of xanthohumol (Xn), a prenylated flavonoid isolated from hops (L.), with a concentration up to 0.96 mg/L in beer. This review aims to summarize the existing studies focusing on the anticancer activity of Xn and its effects on key signaling molecules. Furthermore, the limitations of current studies and challenges for the clinical use of Xn are discussed.

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Sayer Ji
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