Article Publish Status: FREE
Abstract Title:

Electromagnetic Fields, Genomic Instability and Cancer: A Systems Biological View.

Abstract Source:

Genes (Basel). 2019 06 25 ;10(6). Epub 2019 Jun 25. PMID: 31242701

Abstract Author(s):

Jonne Naarala, Mikko Kolehmainen, Jukka Juutilainen

Article Affiliation:

Jonne Naarala


This review discusses the use of systems biology in understanding the biological effectsof electromagnetic fields, with particular focus on induction of genomic instability and cancer. Weintroduce basic concepts of the dynamical systems theory such as the state space and attractors andthe use of these concepts in understanding the behavior of complex biological systems. We thendiscuss genomic instability in the framework of the dynamical systems theory, and describe thehypothesis that environmentally induced genomic instability corresponds to abnormal attractorstates; large enough environmental perturbations can force the biological system to leave normalevolutionarily optimized attractors (corresponding to normal cell phenotypes) and migrate to lessstable variant attractors. We discuss experimental approaches that can be coupled with theoreticalsystems biology such as testable predictions, derived from the theory and experimental methods,that can be used for measuring the state of the complex biological system. We also reviewpotentially informative studies and make recommendations for further studies.

Study Type : Review

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.