Review: Presentations of mixed IgE- and cell-mediated disorders - GreenMedInfo Summary
Clinical presentations of food allergy.
Pediatr Clin North Am. 2011 Apr ;58(2):315-26, ix. PMID: 21453804
Division of Allergy and Immunology, Center for Cancer and Blood Disorders, Children's National Medical Center, 111 Michigan Avenue, North West, Washington, DC 20010, USA.
Food allergies are immune-mediated responses to food proteins. Because of differences in the underlying immunologic mechanisms, there are varying clinical presentations of food allergy. This article discusses the manifestations of IgE-mediated disorders, including urticaria and angioedema, rhinoconjunctivitis, asthma, gastrointestinal anaphylaxis, generalized anaphylaxis, food-dependent exercise-induced anaphylaxis, and oral allergy syndrome. It also reviews the presentations of mixed IgE- and cell-mediated disorders, including atopic dermatitis and eosinophilic gastrointestinal disorders. Finally, the manifestations of cell-mediated food allergies are discussed,including dietary protein-induced proctitis and proctocolitis, food protein-induced enterocolitis syndrome, celiac disease, and food-induced pulmonary hemosiderosis.