A review of the role of morin in neurodegenerative diseases. - GreenMedInfo Summary

Neurodegenerative diseases are likely to be emerged as the second cause of mortality in the world in coming years. NDDs causes tremendous financial burden on the healthcare system along with profound effect on families and patient. Disease-modifying treatment strategies with proven efficacy for these disorders are still lacking. Documentation proved that oxidative stress plays leading role in the pathophysiology of many neurodegenerative disorders. Molecules with good antioxidant profile could be explored for the doctoring of these conditions. Neuroprotective effects of bioflavonoid morin have been well recognized in literature. Morin being super antioxidant compound helped in preventing and curing these disorders by suppression of ROS and by inhibition of multiple targets. In this review we tried to explain various neuropathological conditions with their target sites and neurobiological mechanisms of morin.