Rheumatic fever: A model of autoimmune disease due to molecular mimicry between human and pathogen proteins. - GreenMedInfo Summary

n/a

Abstract Title:

Rheumatic Fever: A Model of Autoimmune Disease due to Molecular Mimicry between Human and Pathogen Proteins.

Abstract Source:

Crit Rev Immunol. 2020 ;40(5):419-422. PMID: 33463953

Abstract Author(s):

Jorge Kalil, Luiza Guilherme

Article Affiliation:

Jorge Kalil

Abstract:

Acute rheumatic fever (ARF) is caused by an autoimmune response to throat infection with Streptococcus pyogenes in individuals who present some susceptibility genes. Rheumatic heart disease (RHD) is the major sequela and can cause heart failure and premature mortality. The disease is mediated by humoral and cellular immune responses. In this review, we present the major events that can trigger heart lesions.

Article Published Date : Dec 31, 2019

Study Type : Review

Additional Links

Diseases : Autoimmune Diseases : CK(9797) : AC(1966), Rheumatic Fever : CK(1) : AC(1)

Additional Keywords : Molecular Mimicry : CK(102) : AC(29)

Print Options

Some features are currently member only features. If you are already a member, please login. Otherwise, click here to become a member.

Printer-friendly version

Rheumatic fever: A model of autoimmune disease due to molecular mimicry between human and pathogen proteins. - GreenMedInfo Summary

Print Options

Key Research Topics

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.