Abstract Title:

[Rhino-cerebral fungal infection successfully treated with supplementary hyperbaric oxygen therapy].

Abstract Source:

Rev Neurol (Paris). 2003 Dec;159(12):1178-80. PMID: 14978421

Abstract Author(s):

N Chassaing, L Valton, M Kany, E Bonnet, E Uro-Coste, M-B Delisle, P Bousquet, G Géraud


Rhino-cerebral fungal infections are rare and difficult disorders to cure. We report the case of a woman presenting a left trigeminal neuralgia complicated by ophthalmoplegia and blindness. MRI demonstrated a lesion of the left orbital apex with extension into the cavernous sinus. Fungal infiltration (aspergillosis or mucormycosis), was seen on biopsy. High-dose liposomal Amphotericin B (5mg/kg/day) for six weeks was unsuccessful. Adjunctant hyperbaric oxygen therapy led to clinical and radiological improvement. Hyperbaric oxygen therapy is discussed in the medical management of rhino-cerebral yeast abscesses.

Study Type : Human Study

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