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Article Publish Status: FREE
Abstract Title:

The Role of Exosomes in the Female Reproductive System and Breast Cancers.

Abstract Source:

Onco Targets Ther. 2020 ;13:12567-12586. Epub 2020 Dec 8. PMID: 33324075

Abstract Author(s):

Yuqi Bai, Jie Guo, Zhongshan Liu, Yunfeng Li, Shunzi Jin, Tiejun Wang

Article Affiliation:

Yuqi Bai

Abstract:

Exosomes are nanoscale extracellular vesicles released by nearly all cell types. Exosomes were originally considered as waste receptacles for discarding unwanted cellular products; however, these organelles are now considered to be important for cell communication by delivering biologically active molecules such as proteins, DNA, non-coding RNA and mRNA. Studies have revealed that exosomes are closely related to several diseases, especially cancers. Exosomes are indispensable for the emergence and progression of tumor. Here, we review the status of research on exosomes in the female reproductive system cancers and breast cancer, focusing on their biological roles in chemical resistance and immune responses, as well as their underlying applications in drug delivery and nanotherapy and as biological markers for tumor diagnosis.

Study Type : Review
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Additional Keywords : Exosomes : CK(376) : AC(226)

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