Abstract Title:

The Role of the Gut-Brain Axis in Attention-Deficit/Hyperactivity Disorder.

Abstract Source:

Gastroenterol Clin North Am. 2019 09 ;48(3):407-431. Epub 2019 Jul 2. PMID: 31383279

Abstract Author(s):

Sarita A Dam, Jeanette C Mostert, Joanna W Szopinska-Tokov, Mirjam Bloemendaal, Maria Amato, Alejandro Arias-Vasquez

Article Affiliation:

Sarita A Dam


Genetic and environmental factors play a role in the cause and development of attention-deficit/hyperactivity disorder (ADHD). Recent studies have suggested an important role of the gut-brain axis (GBA) and intestinal microbiota in modulating the risk of ADHD. Here, the authors provide a brief overview of the clinical and biological picture of ADHD and how the GBA could be involved in its cause. They discuss key biological mechanisms involved in the GBA and how these may increase the risk of developing ADHD. Understanding these mechanisms may help to characterize novel treatment options via identification of disease biomarkers.

Study Type : Review

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