Abstract Title:

Phenolic fraction and nonpolar fraction from sea buckthorn leaves and twigs: chemical profile and biological activity.

Abstract Source:

Future Med Chem. 2018 Sep 27. Epub 2018 Sep 27. PMID: 30257568

Abstract Author(s):

Bartosz Skalski, Bogdan Kontek, Beata Olas, Jerzy Żuchowski, Anna Stochmal

Article Affiliation:

Bartosz Skalski


AIM: The main objective of our studies was to determine the chemical composition and biological activities (antioxidant and anticoagulant properties) of two standardized phenolic fractions from sea buckthorn twig and leaf, and two standardized nonpolar fractions from twig and leaf in human plasma in vitro.

MATERIAL & METHODS:  Appropriately prepared extracts from sea buckthorn twigs and leaves were used. Markers of oxidative stress and hemostasis were determined in this work.

RESULTS: The reduction of plasma lipid peroxidation induced by HO/Fe was observed for two fractions from twig. Analysis of the effect on the coagulation properties of plasma demonstrated that the nonpolar fraction from twig and the phenolic fraction from leaf, significantly prolonged the activated partial thromboplastin time and the prothrombin time, respectively.

CONCLUSION: Sea buckthorn twig and leaf are new promising plant materials in the prophylaxis and treatment of cardiovascular disorders.

Study Type : In Vitro Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2021 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.