Serum ionized magnesium in post-traumatic headaches.
Maturitas. 2005 Jun 16;51(2):177-86. PMID: 11562631
Division of Pediatric Neurology, State University of New York-Health Sciences Center, Brooklyn, New York, USA.
The objective of this study was to determine the values of serum ionized magnesium, total magnesium, and ionized calcium/ionized magnesium ratios in children with headaches. One hundred thirty-five children with primary complaints of headaches were classified according to the criteria of the International Headache Society. Blood samples were obtained and tested for ionized magnesium (IMg(2+)), total magnesium, ionized calcium (ICa(2+)), and pH. The ICa(2+)/IMg(2+) ratio was calculated. Nine children were given a diagnosis of post-traumatic headache. Six of them had statistically significant (P<.05) lowered IMg(2+) levels and high ICa(2+)/IMg(2+) ratios. Abnormalities in serum IMg(2+) concentrations and ICa(2+)/IMg(2+) ratios were found in children with post-traumatic headaches, but total magnesium levels were normal.