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Article Publish Status: FREE
Abstract Title:

Severe COVID-19 patients have severe vitamin D deficiency in Northeast Mexico.

Abstract Source:

Nutr Hosp. 2022 Mar 29 ;39(2):393-397. PMID: 35187940

Abstract Author(s):

Edgar Paolo Rodríguez Vidales, Denise Garza Carrillo, Ana María Salinas Martínez, Olivia Abigail Robles Rodríguez, Roberto Montes de Oca Luna, Consuelo Treviño Garza, Alma Rosa Marroquín Escamilla, Manuel Enrique de la O-Cavazos

Article Affiliation:

Edgar Paolo Rodríguez Vidales

Abstract:

Objective: the association between vitamin D and COVID-19 severity is not consistent. We compared prevalences and analyzed the association between vitamin D deficiency and COVID-19 severity in Northeast Mexico. Methods: this was a cross-sectional study with individuals consecutively included at a referral diagnostic center during March-September 2020 (n = 181). Concurrently, every patient admitted to intensive care was also consecutively included (n = 116). Serum 25(OH)D<20 ng/mL was considered vitamin D deficiency. Descriptive, ANOVA, and multivariate ordinal regression analyses were performed. Results: vitamin D deficiency prevalence was 63.8 % (95 % CI, 54.7, 72.0) in severe COVID-19; 25.6 % (95 % CI, 17.4, 36.0) in mild COVID-19; and 42.4 % (95 % CI, 33.2, 52.3) in non-diseased individuals. Vitamin D deficiency increased 5 times the odds of severe COVID-19 (95 % CI, 1.1, 24.3), independently of sex, age, body mass index, and inflammatory markers. Conclusions: this study is the first report of vitamin D deficiency in Northeast Mexico. Vitamin D deficiency was associated with COVID-19 severity.

Study Type : Human Study

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