Severe oral ulceration has occurred with the use of alendronate without inappropriate therapeutic administration of the medication. - GreenMedInfo Summary
Oral ulcer associated with alendronate: a case report.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jul 29. Epub 2010 Jul 29. PMID: 20674418
Senior House Officer, Department of Oral and Maxillofacial Surgery, Central Hospital, Västerås, Sweden.
Irritation of the mucosa of the aerodigestive tract is a well-known adverse effect of alendronate, whereas oral ulceration has been reported in only 14 articles in both the English and non-English literature. All of these have been associated with misuse of the drug. We here present the first case of severe oral ulceration attributable to use of alendronate without inappropriate therapeutic administration of the medication.