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Article Publish Status: FREE
Abstract Title:

Short-Term Exposure to Ambient Air Pollution and Hospital Admissions for Sequelae of Stroke in Chinese Older Adults.

Abstract Source:

Geohealth. 2022 Nov ;6(11):e2022GH000700. Epub 2022 Nov 1. PMID: 36447746

Abstract Author(s):

Rui Wang, Ruijun Xu, Jing Wei, Tingting Liu, Yunshao Ye, Yingxin Li, Qiaoxuan Lin, Yun Zhou, Suli Huang, Ziquan Lv, Qi Tian, Yuewei Liu

Article Affiliation:

Rui Wang

Abstract:

Extensive evidence suggests that ambient air pollution contributes to a higher risk of hospital admissions for cerebrovascular diseases; however, its association with admissions for sequelae of stroke remains unclear. A time-stratified case-crossover study was conducted among 31,810 older adults who were admitted to hospital for sequelae of stroke in Guangzhou, China during 2016-2019. For each subject, daily residential exposure to fine particulate matter (PM), inhalable particulate matter (PM), sulfur dioxide (SO), nitrogen dioxide (NO), carbon monoxide (CO), and ozone (O) was extracted from a validated grid data set. Conditional logistic regression models were used for exposure-response analyses. In single-pollutant models, each interquartile range (IQR) increase of lag 04-day exposure to CO (IQR: 0.25 mg/m) and lag 3-day exposure to O(69.6 μg/m) was significantly associated with a 4.53% (95% confidence interval: 1.67%, 7.47%) and 5.63% (1.92%, 9.48%) increase in odds of hospital admissions for sequelae of stroke, respectively. These associations did not significantly vary across age or sex. With further adjustment for each of the other pollutants in 2-pollutant models, the association for CO did not change significantly, while the association for Odisappeared. We estimated that 7.72% of the hospital admissions were attributable to CO exposures. No significant or consistent association was observed for exposure to PM, PM, SO, or NO. In conclusion, short-term exposure to ambient CO, even at levels below the WHO air quality guideline, was significantly associated with an increased odds of hospital admissions for sequelae of stroke, which may lead to considerable excess hospital admissions.

Study Type : Human Study

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