Article Publish Status: FREE
Abstract Title:

A Single Dose of The Mango Leaf Extract Zynamitein Combination with Quercetin Enhances Peak Power Output During Repeated Sprint Exercise in Men and Women.

Abstract Source:

Nutrients. 2019 Oct 28 ;11(11). Epub 2019 Oct 28. PMID: 31661850

Abstract Author(s):

Miriam Gelabert-Rebato, Marcos Martin-Rincon, Victor Galvan-Alvarez, Angel Gallego-Selles, Miriam Martinez-Canton, Tanausú Vega-Morales, Julia C Wiebe, Constanza Fernandez-Del Castillo, Elizabeth Castilla-Hernandez, Oriana Diaz-Tiberio, Jose A L Calbet

Article Affiliation:

Miriam Gelabert-Rebato


The mango leaf extract rich in mangiferin Zynamiteimproves exercise performance when combined with luteolin or quercetin ingested at least 48 h prior to exercise. To determine whether a single dose of Zynamiteadministered 1 h before exercise increases repeated-sprint performance, 20 men and 20 women who were physically active were randomly assigned to three treatments following a double-blind cross-over counterbalanced design. Treatment A, 140 mg of Zynamite, 140 mg of quercetin, 147.7 mg of maltodextrin, and 420 mg of sunflower lecithin; Treatment B, 140 mg of Zynamite, 140 mg of quercetin, and 2126 mg of maltodextrin and Treatment C, 2548 mg of maltodextrin (placebo). Subjects performed three Wingate tests interspaced by 4 min and a final 15 s sprint after ischemia. Treatments A and B improved peak power output during the first three Wingates by 2.8% and 3.8%, respectively (treatment x sprint interaction,= 0.01). Vastus Lateralis oxygenation (NIRS) was reduced, indicating higher Oextraction (treatment× sprint interaction,= 0.01). Improved Oextraction was observed in the sprints after ischemia (= 0.008; placebo vs. mean of treatments A and B). Blood lactate concentration was 5.9% lower after the ingestion of Zynamite® with quercetin in men (treatment by sex interaction,= 0.049). There was a higher Vastus Lateralis Oextraction during 60 s ischemia with polyphenols (treatment effect,= 0.03), due to the greater muscle VOin men (= 0.001). In conclusion, a single dose of Zynamitecombined with quercetin one hour before exercise improves repeated-sprint performance and muscle Oextraction and mitochondrial Oconsumption during ischemia. No advantage was obtained from the addition of phospholipids.

Study Type : Human Study

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