Article Publish Status: FREE
Abstract Title:

On site assessment of cardiac function and neural regulation in amateur half marathon runners.

Abstract Source:

Open Heart. 2014 ;1(1):e000005. Epub 2014 Feb 11. PMID: 25332775

Abstract Author(s):

Laura Dalla Vecchia, Egidio Traversi, Alberto Porta, Daniela Lucini, Massimo Pagani

Article Affiliation:

Laura Dalla Vecchia


OBJECTIVE: Strenuous exercise variably modifies cardiovascular function. Only few data are available on intermediate levels of effort. We therefore planned a study in order to address the hypothesis that a half marathon distance would result in transient changes of cardiac mechanics, neural regulation and biochemical profile suggestive of a complex, integrated adaptation.

METHODS: We enrolled 35 amateur athletes (42±7 years). Supine and standing heart rate variability and a complete echocardiographic evaluation were assessed on site after the completion of a half marathon (postrace) and about 1 month after (baseline). Biochemical tests were also measured postrace.

RESULTS: Compared to baseline, the postrace left ventricular end-diastolic volume was smaller, peak velocity of E wave was lower, peak velocity of A wave higher, and accordingly the E/A ratio lower. The postrace heart and respiratory rate were higher and variance of RR interval lower, together with a clear shift towards a sympathetic predominance in supine position and a preserved response to orthostasis. At baseline, athletes were characterised by a lower, although still predominant, sympathetic drive with a preserved physiological response to standing.

CONCLUSIONS: Immediately after a half marathon there are clear marks that an elevated sympathetic cardiac drive outlasts the performance, together with decreased left ventricular diastolic volumes and slight modifications of the left ventricular filling pattern without additional signs of diastolic dysfunction or indices of transient left or right ventricular systolic abnormalities. Furthermore, no biochemical indices of any permanent cardiac damage were found.

Study Type : Human Study
Additional Links
Additional Keywords : Half-Marathon

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