Abstract Title:

Bioactive steroidal saponins from Smilax medica.

Abstract Source:

Planta Med. 2006 Jun;72(7):667-70. Epub 2006 May 29. PMID: 16732531

Abstract Author(s):

M Sautour, T Miyamoto, M-A Lacaille-Dubois


Full Citation: "Two new spirostanol saponins ( 1 and 2) were isolated from the roots of Smilax medica, together with the known smilagenin 3-O-beta-D-glucopyranoside (3). Their structures were determined by spectroscopic methods including 1D- and 2D-NMR experiments. Compounds 1 and 2 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (MICs between 6.25 and 50 microg/mL) whereas 3 was inactive."

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