Abstract Title:

Some patients with NHL possessed immunoreactivity to gliadin and to cow's milk proteins.

Abstract Source:

Int J Hematol. 2009 Sep ;90(2):212-6. Epub 2009 Jul 17. PMID: 19609644

Abstract Author(s):

Zorica D Juranić, Irina Besu, Svetislav Jelić, Aleksandra Konić-Ristić, Suzana Matković, Ljiljana Janković, Dusica Gavrilović, Branka Radojcić, Ivana Minić

Article Affiliation:

Institute of Oncology and Radiology of Serbia, Pasterova 14, Belgrade, Serbia. [email protected]


Non-Hodgkin lymphoma (NHL) represents heterogeneous group of diseases either B, or T cell origin. In order to assess whether food antigens contribute to the imbalance of immune response, the aim of this work was screening the sera of patients with (mostly) B cell NHL, and of people with non-malignant health disorders (NMD), as well as of healthy people for their immunoreactivity to food constituent gliadin, and to cow's milk proteins. Data obtained by ELISA tests show the existence of the enhanced immunoreactivity to food antigens in some NHL patients, as well as in some people with NMD. The high degree of coincidence in the presence of enhanced levels of immune complexes in circulation (CIC) and of immunoreactivity with gliadin in immunofixation (after the serum protein electrophoresis in agarose gel in veronal buffer, at pH 8.6) especially in NHL patients points that some antigliadin immunoreactivity unrevealed in ELISA tests could be hidden in CIC. This, only in the presence of malignant genotype, as well as the enhanced levels of CIC in some of NHL patients could both, at least partially contribute to the persistent non-specific support of disease. They call for the new research of the clinical importance of both, the elevated humoral immunity to food antigens (gluten, cow's milk proteins) for the course of this very severe hematological disease.

Study Type : Human Study
Additional Links
Problem Substances : Gliadin : CK(821) : AC(118)
Adverse Pharmacological Actions : Immunoreactive : CK(237) : AC(54)

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.