Abstract Title:

Spirulina supplementation during gradual weight loss in competitive wrestlers.

Abstract Source:

Br J Nutr. 2021 Mar 15:1-21. Epub 2021 Mar 15. PMID: 33715648

Abstract Author(s):

Reza Bagheri, Raoof Negaresh, Mohamad S Motevalli, Alexei Wong, Damoon Ashtary-Larky, Mehdi Kargarfard, Amir Rashidlamir

Article Affiliation:

Reza Bagheri


We aimed to assess the effects of spirulina supplementation during gradual weight loss on serum concentrations of follistatin (FST), myostatin (MST), insulin-like growth factor 1 (IGF-1), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and body composition in competitive wrestlers. Forty competitive wrestlers (age: 22± 2 years) were randomly assigned to one of two groups: gradual weight loss + spirulina (SP; n=20) or gradual weight loss + placebo (PL; n=20). Subjects in both groups lost weight according to a designed diet over 12 days and were required to reduce baseline body mass by 4%. Subjects in the SP group received two tablets of spirulina, while subjects in the PL received two tablets of placebo before each meal. Concentrations of mentioned serum markers and body composition were measured before and after the interventions. Body mass (SP = -3.1 kg and PL= -2.9 kg), body fat percentage (SP = -2.1 %and PL= -0.6 %), fat mass (SP = -2.2 kg and PL= -0.9 kg), and skeletal muscle mass (SP = -1.4 kg and PL= -1.5 kg) significantly decreased in both groups (P<0.05). The changes in body fat percentage and fat mass were significantly greater in SP compared to the PL group (P<0.001). Additionally, MST (SP = -0.1 ng/ml), AST (SP = -2.1 u/l), and ALT (SP = -2.7 u/l) concentrations significantly diminished in SP group (P=0.005) while FST (PL = -0.1 ng/ml) and IGF-1 (PL = -2.6 ng/ml) concentrations significantly decreased in PL group (P<0.05). Spirulina supplementation during gradual weight loss is beneficial in reducing body fat percentage, fat mass, MST, and liver enzymes while maintaining IGF-1 and FST concentrations in competitive wrestlers.

Study Type : Human Study
Additional Links
Therapeutic Actions : Weight Reduction : CK(71) : AC(8)

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.