Spontaneous compartment syndrome in association with simvastatin-induced myositis.
Emerg Med J. 2008 May ;25(5):305-6. PMID: 18434476
Department of Orthopaedics, Edinburgh Royal Infirmary, Little France, Dalkeith Road, Edinburgh EH16 4SU, UK.
Compartment syndrome as a result of simvastatin-induced myositis is extremely rare. This case discusses a patient with spontaneous onset compartment syndrome that necessitated four-compartment fasciotomy. A thorough investigation into its cause highlighted statin-induced myositis as the most likely aetiological agent. When investigating a patient with unexplained spontaneous compartment syndrome it is important to consider drug-induced myositis. This case reinforces the difficulty faced in diagnosing spontaneous compartment syndrome.