Abstract Title:

Statin-associated myasthenia gravis: report of 4 cases and review of the literature.

Abstract Source:

Medicine (Baltimore). 2006 Mar ;85(2):82-5. PMID: 16609346

Abstract Author(s):

Valerie Purvin, Aki Kawasaki, Kyle H Smith, Anat Kesler

Article Affiliation:

Midwest Eye Institute, Indianapolis, Indiana 46280, USA. [email protected]


A few recent individual case reports have suggested that a myasthenic syndrome may be associated with statin treatment, but this association is not well described. We report 4 patients who developed symptoms of myasthenia gravis within 2 weeks of starting treatment with a statin drug. In 1 case the drug appears to have exacerbated underlying myasthenic weakness, whereas in the other 3 cases, de novo antibody formation appears to be most likely. In each case, some degree of recovery followed discontinuation of the statin medication.

Study Type : Human: Case Report

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