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Abstract Title:

Thimerosal exposure in early life and neuropsychological outcomes 7-10 years later.

Abstract Source:

J Pediatr Psychol. 2012 Jan-Feb;37(1):106-18. Epub 2011 Jul 23. PMID: 21785120

Abstract Author(s):

John P Barile, Gabriel P Kuperminc, Eric S Weintraub, Jonathan W Mink, William W Thompson

Article Affiliation:

John P Barile

Abstract:

OBJECTIVE: The authors used a public use data set to investigate associations between the receipt of thimerosal-containing vaccines and immune globulins early in life and neuropsychological outcomes assessed at 7-10 years.

METHODS: The data were originally created by evaluating 1,047 children ages 7-10 years and their biological mothers. This study developed seven latent neuropsychological factors and regressed them on a comprehensive set of covariates and thimerosal exposure variables.

RESULTS: The authors found no statistically significant associations between thimerosal exposure from vaccines early in life and six of the seven latent constructs. There was a small, but statistically significant association between early thimerosal exposure and the presence of tics in boys.

CONCLUSIONS: This finding should be interpreted with caution due to limitations in the measurement of tics and the limited biological plausibility regarding a causal relationship.

Study Type : Human Study
Additional Links
Anti Therapeutic Actions : Vaccination: All : CK(12676) : AC(1344)
Problem Substances : Thimerosal : CK(799) : AC(190)

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