Article Publish Status: FREE
Abstract Title:

[Role of sulforaphane in improving negative symptoms and cognitive symptoms of schizophrenia and the underlying mechanism].

Abstract Source:

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Jun 28 ;44(6):701-705. PMID: 31304933

Abstract Author(s):

Ye Yang, Ranran Li, Gangrui Hei, Renrong Wu

Article Affiliation:

Ye Yang


The negative symptoms and cognitive symptoms of schizophrenia patients are still clinical problems to be solved. Schizophrenia patients are abnormal in oxidative stress, immune regulation, and anti-histone deacetylase (HDAC), while sulforaphane plays a role in anti-oxidative stress, anti-inflammation, and anti-HDAC. Therefore, the sulforaphane could improve the negative symptoms and cognitive deficits of schizophrenia.

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