[Role of sulforaphane in improving negative symptoms and cognitive symptoms of schizophrenia and the underlying mechanism].
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2019 Jun 28 ;44(6):701-705. PMID: 31304933
The negative symptoms and cognitive symptoms of schizophrenia patients are still clinical problems to be solved. Schizophrenia patients are abnormal in oxidative stress, immune regulation, and anti-histone deacetylase (HDAC), while sulforaphane plays a role in anti-oxidative stress, anti-inflammation, and anti-HDAC. Therefore, the sulforaphane could improve the negative symptoms and cognitive deficits of schizophrenia.