Abstract Title:

Biosynthesized tea polyphenols inactivate Chlamydia trachomatis in vitro.

Abstract Source:

Antimicrob Agents Chemother. 2005 Jun;49(6):2501-3. PMID: 15917555

Abstract Author(s):

Tsutomu Yamazaki, Toshio Kishimoto, Sadashi Shiga, Kozue Sato, Toshikatsu Hagiwara, Miyuki Inoue, Nozomu Sasaki, Kazunobu Ouchi, Yukihiko Hara


Biosynthesized tea polyphenols showed antichlamydial activity against Chlamydia trachomatis D/UW-3/Cx and L2/434/Bu using cell culture. The most active compounds were (-)-epigallocatechin gallate and (-)-epicatechin gallate, followed by (-)-epicatechin (EC). (+)-Epicatechin and (-)-epigallocatechin were intermediate. EC was the least toxic. These results warrant evaluation of tea polyphenols as topical antichlamydial agents.

Study Type : In Vitro Study

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Sayer Ji
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