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Article Publish Status: FREE
Abstract Title:

The Impact of Bisphenol A on Fertility, Reproductive System, and Development: A Review of the Literature.

Abstract Source:

Int J Endocrinol. 2019 ;2019:4068717. Epub 2019 Apr 10. PMID: 31093279

Abstract Author(s):

Ewa Matuszczak, Marta Diana Komarowska, Wojciech Debek, Adam Hermanowicz

Article Affiliation:

Ewa Matuszczak

Abstract:

Bisphenol A (BPA) has been used since the 1950s, in food packaging, industrial materials, dental sealants, and personal hygiene products. Everyone is exposed to BPA through skin, inhalation, and digestive system. BPA disrupts endocrine pathways, because it has weak estrogenic, antiandrogenic, and antithyroid activities. Despite the rapid metabolism, BPA can accumulate in different tissues. Many researchers proved the impact of BPA on human development, metabolism, and finally reproductive system. There is increasing evidence that BPA has impact on human fertility and is responsible for the reproductive pathologies, e.g., testicular dysgenesis syndrome, cryptorchidism, cancers, and decreased fertility in male and follicle loss in female.

Study Type : Review

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