These results suggest that H. erinaceus has preventive and therapeutic potentials in managing memory deficits. - GreenMedInfo Summary

() is a rare and appreciated fungal species belonging to the divisionused for centuries in traditional Chinese medicine for its medicinal value. This species of mushrooms brings the most diverse benefits for the human body, and can have beneficial effects for treating Alzheimer's disease (AD). This study investigated whether ethanolic extract from the fungal biomass ofenhances cognitive function via the action on cholinergic neurons using the scopolamine (SCOP)-induced zebrafish () model of memory impairment. The ethanolic extract from the fungal biomass ofwas previously obtained using an ultrasonic extraction method (UE). The administration ofextract to zebrafish, with a pattern of AD induced by scopolamine, showed an improvement in memory evaluated by behavioral and biochemical tests on brain tissue. These results suggest thathas preventive and therapeutic potentials in managing memory deficits and brain oxidative stress in zebrafish with AD.