Article Publish Status: FREE
Abstract Title:

The effect of leg hyperthermia using far infrared rays in bedridden subjects with type 2 diabetes mellitus.

Abstract Source:

Acta Med Okayama. 2010 Apr ;64(2):143-7. PMID: 20424670

Abstract Author(s):

Akihiko Kawaura, Noritoshi Tanida, Masato Kamitani, Junichi Akiyama, Masatoshi Mizutani, Naoko Tsugawa, Toshio Okano, Eiji Takeda

Article Affiliation:

Akihiko Kawaura


We examined the effect of leg hyperthermia on oxidative stress in bedridden subjects with type 2 diabetes mellitus using 15-min sessions of far infrared rays over a two-week period. Four subjects (male 1, female 3) incapacitated by a stroke were recruited for this study. All patients were admitted to Takahashi Central Hospital and ate the same hospital meals. Fasting plasma glucose, HbA1c, tumor necrosis factor (TNF)alpha, free fatty acid, leptin, adiponectin and plasma 8-epi-prostaglandin F2alpha (8-epi-PGF2alpha) levels as a marker of oxidative stress were measured on admission, just before and 2 weeks after local heating of the leg. Results showed that plasma total 8-epi-PGF2alpha levels were decreased significantly while TNFalpha levels were increased significantly. On the other hand, glucose, HbA1c, free fatty acid, leptin and adiponectin levels were not changed during the study period. These results suggest that repeated leg hyperthermia may protect against oxidative stress.

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