Abstract Title:

Acute and chronic flow-mediated dilation and blood pressure responses to daily intake of boysenberry juice: a preliminary study.

Abstract Source:

Int J Food Sci Nutr. 2013 Dec ;64(8):988-92. Epub 2013 Jul 12. PMID: 23848379

Abstract Author(s):

Akito Matsusima, Ryo Furuuchi, Yoshiko Sakaguchi, Hiroshi Goto, Tadayuki Yokoyama, Hiroshi Nishida, Masao Hirayama

Article Affiliation:

Akito Matsusima


There is an increasing interest in dietary polyphenols for risk reduction in cardiovascular diseases. The aim of this study was to evaluate acute and chronic flow-mediated dilation (FMD) and blood pressure responses to daily intake of boysenberry juice. FMD of the brachial artery was measured in six subjects in the initial, intermediate and follow-up stages of a 4-week open-label intervention study. The intake of boysenberry juice (180 ml/d) increased FMD with progression of intervention stage, and FMD differed in the follow-up stage compared with pre-intake baseline (p = 0.0163 < 0.0167 = 0.1/6) using Bonferroni correction. Changes in systolic blood pressure (SBP) correlated negatively with SBP before intake only in the follow-up stage (r = -0.961 and p = 0.0007 at 3.5 h), indicating a greater SBP reduction in subjects with higher SBP. These results suggestthat daily intake of boysenberry juice is beneficial for reducing cardiovascular risk.

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