Article Publish Status: FREE
Abstract Title:


Abstract Source:

Afr J Tradit Complement Altern Med. 2017 ;14(2):1-8. Epub 2017 Jan 13. PMID: 28573216

Abstract Author(s):

Houda Ben Jemaa, Amani Ben Jemia, Sarra Khlifi, Halima Ben Ahmed, Fethi Ben Slama, Anis Benzarti, Jalila Elati, Abdallah Aouidet

Article Affiliation:

Houda Ben Jemaa


BACKGROUND: Diabetes mellitus is one of the most common endocrinal disorders and medicinal plants continue to play an important role in the management of this disease. In this study, Rosa canina was investigated for the antioxidant andα-amylase inhibition activities.

MATERIALS AND METHODS: Methanolic extract of Rosa canina was investigated for its potential antioxidant activity. The extracts' total phenolic and flavonoid contents and scavenging capacity for free radicals were evaluated. Theα-amylase inhibition assay was also carried.

RESULTS: Rosa canina extract exhibits a total Phenolic and flavonoid levels respectively (21.918 mg GAE/g and 2.647mg ER/g). The free radical scavenging activity was found to be prominent against DPPH with an IC50 of 0.668 mg/ml and against ABTS with an IC50 of 0.467 mg/ml. Extract showed a significant ferric ion reducing activities with an IC50 of4.962 mg/ml.

CONCLUSION: Rosa canina exerted a higher inhibitory activity againstα-amylase. The obtained results support the antidiabetic use of rosa canina.

Study Type : In Vitro Study

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