Abstract Title:

In Vitro Antimicrobial Activity of Thymus vulgaris Essential Oil Against Major Oral Pathogens.

Abstract Source:

J Evid Based Complementary Altern Med. 2017 Jan 1:2156587217700772. Epub 2017 Jan 1. PMID: 28397552

Abstract Author(s):

Mohammadmehdi Fani, Jamshid Kohanteb

Article Affiliation:

Mohammadmehdi Fani


The objective of present investigation was to determine antimicrobial activity of Thymus vulgaris oil on some oral pathogens. Thymus vulgaris oil was prepared by hydrodistillation and tested against 30 clinical isolates of each of Streptococcus pyogenes, Streptococcus mutans, Candida albicans, Porphyromonas gingivalis, and Aggregatibacter actinomycetemcomitans, prepared from related oral infections using agar disk diffusion and broth microdilution methods. Thymus vulgaris oil at concentrations of 16 to 256μg/mL exhibited strong inhibitory activity on all clinical isolates producing inhibition zones of 7.5 to 42 mm as measured by agar disk diffusion method. Streptococcus pyogenes and Streptococcus mutans were the most sensitive isolates with minimum inhibitory concentrations of 1.9 and 3.6 μg/mL, respectively. The minimum inhibitory concentration values for C albicans, A actinomycetemcomitans, and P gingivalis were 16.3, 32, and 32 μg/mL, respectively.

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