Article Publish Status: FREE
Abstract Title:

Trends in the Immunomodulatory Effects of: Total Extracts, Polysaccharides and Cordycepin.

Abstract Source:

Front Pharmacol. 2020 ;11:575704. Epub 2020 Nov 30. PMID: 33328984

Abstract Author(s):

Chun-Ting Lee, Keng-Shiang Huang, Jei-Fu Shaw, Jung-Ren Chen, Wen-Shuo Kuo, Gangxu Shen, Alexandru Mihai Grumezescu, Alina Maria Holban, Yi-Ting Wang, Jun-Sheng Wang, Yi-Ping Hsiang, Yu-Mei Lin, Hsiao-Han Hsu, Chih-Hui Yang

Article Affiliation:

Chun-Ting Lee


() is a fungus with a long history of widespread use in folk medicine, and its biological and medicinal functions are well studied. A crucial pharmacological effect ofis immunomodulation. In this review, we catalog the immunomodulatory effects of different extracts of, namely total extracts, polysaccharides and cordycepinTotal extracts obtained using water or 50% ethyl alcohol and polysaccharides fromwere discovered to tend to promote type 1 immunity, whereas total extracts obtained using 70-80% ethyl alcohol and cordycepin fromwere more likely to promote type 2 immunity. This article is the first to classify the immunomodulatory effects of different extracts of. In addition, we discovered a relationship between different segments or extracts and differing types of immunity. This review can provide the readers a comprehensive understanding on the immunomodulatory effects of the precious folk medicine and guidance on its use for both health people and those with an immunodeficiency.

Study Type : Review
Additional Links
Pharmacological Actions : Immunomodulatory : CK(4048) : AC(1475)

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