Abstract Title:

Demethoxycurcumin and its semisynthetic analogues as antitubercular agents.

Abstract Source:

Planta Med. 2008 Dec;74(15):1828-31. Epub 2008 Nov 7. PMID: 18991209

Abstract Author(s):

Dinesh Kumar Agrawal, Dharmendra Saikia, Richa Tiwari, Shweta Ojha, Karuna Shanker, Jonnala Kotesh Kumar, Anil Kumar Gupta, Sudeep Tandon, Arvind Singh Negi, Suman Preet Khanuja


Demethoxycurcumin, isolated from the rhizomes of Curcuma longa, was found to possess antitubercular activity against Mycobacterium tuberculosis H (37)Rv strain at 200 microg/mL. Derivatisation of this active principle yielded a potent agent 6, exhibiting considerable activity with a minimum inhibitory concentration (MIC) value of 7.8 microg/mL. H (37)Rv:Mycobacterium tuberculosis H (37)Rv strain MIC:minimum inhibitory concentration.

Study Type : In Vitro Study

Print Options

Key Research Topics

Sayer Ji
Founder of GreenMedInfo.com

Subscribe to our informative Newsletter & get Nature's Evidence-Based Pharmacy

Our newsletter serves 500,000 with essential news, research & healthy tips, daily.

Download Now

500+ pages of Natural Medicine Alternatives and Information.

This website is for information purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional.

© Copyright 2008-2022 GreenMedInfo.com, Journal Articles copyright of original owners, MeSH copyright NLM.